Primary progressive aphasia: clinical, imaging, and neuropathological findings
- PMID: 20124255
- PMCID: PMC10845457
- DOI: 10.1177/1533317509356691
Primary progressive aphasia: clinical, imaging, and neuropathological findings
Abstract
Primary Progressive Aphasia (PPA) is a neurodegenerative disorder initially presenting with progressive language imapirment. This article provides a clinically oriented review of PPA. Different clinical presentations and imaging findings of 3 subtypes, agrammatic, semantic and logopenic, are presented. Underlying neuropathology, medical and social management aspects of these patients are reviewed.
Similar articles
-
The new classification of primary progressive aphasia into semantic, logopenic, or nonfluent/agrammatic variants.Curr Neurol Neurosci Rep. 2010 Nov;10(6):484-90. doi: 10.1007/s11910-010-0140-4. Curr Neurol Neurosci Rep. 2010. PMID: 20809401 Free PMC article. Review.
-
Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia.JAMA Neurol. 2018 Mar 1;75(3):342-352. doi: 10.1001/jamaneurol.2017.4309. JAMA Neurol. 2018. PMID: 29309493 Free PMC article.
-
Cognition and anatomy in three variants of primary progressive aphasia.Ann Neurol. 2004 Mar;55(3):335-46. doi: 10.1002/ana.10825. Ann Neurol. 2004. PMID: 14991811 Free PMC article.
-
Syntactic and morphosyntactic processing in stroke-induced and primary progressive aphasia.Behav Neurol. 2013;26(1-2):35-54. doi: 10.3233/BEN-2012-110220. Behav Neurol. 2013. PMID: 22713394 Free PMC article.
-
Primary Progressive Aphasia and Stroke Aphasia.Continuum (Minneap Minn). 2018 Jun;24(3, BEHAVIORAL NEUROLOGY AND PSYCHIATRY):745-767. doi: 10.1212/CON.0000000000000618. Continuum (Minneap Minn). 2018. PMID: 29851876 Free PMC article. Review.
References
-
- Serieux P. Sur un cas de surtide verbale pure. Revue de Medecine. 1893;13:733-750.
-
- Mesulam MM Slowly progressive aphasia without generalized dementia. Ann Neurol. 1982;11(6):592-598. - PubMed
-
- Mesulam MM Primary progressive aphasia-differentiation from Alzheimer’s disease . Ann Neurol. 1987;22(4):533-534. - PubMed
-
- Mesulam MM Primary progressive aphasia: a 25-year retrospective. Alzheimer Dis Assoc Disord. 2007;21(4):S8-S11. - PubMed
-
- Mesulam M., Weintraub S. Primary progressive aphasia and kindred disorders. In: Aminoff MJ, Boller F, Swaab DF, eds. Handbook of Clinical Neurology; vol 89. Amsterdam: Elsevier; 2008:573-587. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources