Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2010 Winter;40(1):49-52.

Discrepancies between two automated immunoassay systems in determining hepatitis B virus markers in serum samples with concomitant presence of antigens and antibodies

Liming Cheng  1 , Qing Guan, Junxia Zhang, Ziyong Sun
Affiliations
  • PMID: 20124330
Comparative Study

Discrepancies between two automated immunoassay systems in determining hepatitis B virus markers in serum samples with concomitant presence of antigens and antibodies

Liming Cheng et al. Ann Clin Lab Sci. 2010 Winter.

Abstract

This study compared the assay results of HBV markers obtained with two automated immunoassay systems in serum samples with concomitant HBV antigens and antibodies. Eighty-nine samples of concomitant HBsAg and anti-HBs and 74 samples of concomitant HBeAg and anti-HBe were analyzed by the Abbott Architect i2000 and the Roche Elecsys 2010 immunoassay systems. The overall concordance rates of the Architect and Elecsys results were 78.6% for samples with concomitant HBsAg and anti-HBs and 77% for samples with concomitant HBeAg and anti-HBe. The data show that substantial differences exist between the results obtained by these two systems, especially in determining anti-HBs and HBeAg at low concentrations.

PubMed Disclaimer

Publication types