Dyslipidemia in newly diagnosed diabetes mellitus: the Jakarta primary non-communicable disease risk factors surveillance 2006

Abstract

Aim: To obtain the prevalence of dyslipidemia and other cardiovascular risk factors in subjects with undiagnosed DM in Jakarta, Indonesia.

Methods: Data were obtained from surveillance of primary non-communicable disease in five regions in Jakarta, Indonesia, conducted in 2006. Targeting for 1,800 samples, we performed a purposive and simple random sampling of subjects within the age range of 25-64 years old in selected sampling areas, and stratified random sampling by adjusting to age and sex within those selected sampling areas. DM was diagnosed according to WHO criteria after an oral glucose test, i.e fasting blood glucose > or = 126 mg/dL or post loading blood glucose > or = 200 mg/dL and subjects had no history of DM. Dyslipidemia was diagnosed if triglyceride > or = 150 mg/dL, HDL-cholesterol in men < 40 mg/dL or < 50 mg/dL in women and total cholesterol > or = 200 mg/dL.

Results: From 1,591 subjects, comprising 640 men and 951 women, the prevalence of newly diagnosed DM is 8.4%. Among this subjects, the prevalences of hypercholesterolemia, hypertriglyceridemia and low HDL-cholesterol are 66.1 (OR 2.28; P=0.004), 54.3 (OR 3.02; P= 0.0001) and 38.6% (OR 2.27; P=0.009) respectively. The prevalence of dyslipidemia in subjects with newly diagnosed DM remains higher among all age groups than that in subjects without DM.

Conclusion: the prevalence of dyslipidemia among subjects with newly diagnosed DM is higher than that in subjects without DM.