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Case Reports
. 1991 Apr;34(4):493-5.
doi: 10.1002/art.1780340416.

Severe fibromyalgia after hypophysectomy for Cushing's disease

P Disdier  1 , J R Harle, T Brue, P Jaquet, P Chambourlier, F Grisoli, P J Weiller
Affiliations
Case Reports

Severe fibromyalgia after hypophysectomy for Cushing's disease

P Disdier et al. Arthritis Rheum. 1991 Apr.

Abstract

We report a case of fibromyalgia occurring after hypophysectomy for Cushing's disease. Clinical examination revealed tender points at 12 of the 18 tender point sites described in the American College of Rheumatology 1990 criteria for the classification of fibromyalgia. The cause of fibromyalgia remains unknown. In our patient, hypophysectomy may have played a role by disturbing endorphin secretion and pain modulation.

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