Westward ho! Pioneering mouse models for x-linked infantile spasms syndrome
- PMID: 20126336
- PMCID: PMC2812720
- DOI: 10.1111/j.1535-7511.2009.01343.x
Westward ho! Pioneering mouse models for x-linked infantile spasms syndrome
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Targeted loss of Arx results in a developmental epilepsy mouse model and recapitulates the human phenotype in heterozygous females.Brain. 2009 Jun;132(Pt 6):1563-76. doi: 10.1093/brain/awp107. Epub 2009 May 12. Brain. 2009. PMID: 19439424 Free PMC article.
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A triplet repeat expansion genetic mouse model of infantile spasms syndrome, Arx(GCG)10+7, with interneuronopathy, spasms in infancy, persistent seizures, and adult cognitive and behavioral impairment.J Neurosci. 2009 Jul 8;29(27):8752-63. doi: 10.1523/JNEUROSCI.0915-09.2009. J Neurosci. 2009. PMID: 19587282 Free PMC article.
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