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. 1991 Apr 9;30(14):3576-82.
doi: 10.1021/bi00228a031.

Mechanistic stoichiometry of mitochondrial oxidative phosphorylation

P C Hinkle  1 , M A Kumar, A Resetar, D L Harris
Affiliations

Mechanistic stoichiometry of mitochondrial oxidative phosphorylation

P C Hinkle et al. Biochemistry. .

Abstract

P/O ratios of rat liver mitochondria were measured with particular attention to systematic errors. Corrections for energy loss during oxidative phosphorylation were made by measurement of respiration as a function of mitochondrial membrane potential. The corrected values were close to 1, 0.5, and 1 at the three coupling sites, respectively. These values are consistent with recent measurements of mitochondrial proton transport.

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