Review
doi: 10.1016/j.ccr.2009.12.029.
All you need is a Mir-acle: the role of nontranslated RNAs in the suppression of B cell chronic lymphocytic leukemia
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- PMID: 20129242
- DOI: 10.1016/j.ccr.2009.12.029
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Review
All you need is a Mir-acle: the role of nontranslated RNAs in the suppression of B cell chronic lymphocytic leukemia
Cancer Cell.
.
Free article
Abstract
miR-15a and miR-16-1 were the first microRNAs linked to cancer because their genes are commonly deleted in human chronic lymphocytic leukemia (CLL). In this issue of Cancer Cell, Klein and coworkers show that deleting a region with these genes in mouse provides a faithful model for human CLL.
Copyright (c) 2010 Elsevier Inc. All rights reserved.
Comment on
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The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia.Cancer Cell. 2010 Jan 19;17(1):28-40. doi: 10.1016/j.ccr.2009.11.019. Epub 2010 Jan 7. Cancer Cell. 2010. PMID: 20060366
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