Variation of genes encoding GGPLs syntheses among Mycoplasma fermentans strains
- PMID: 20134120
- DOI: 10.1292/jvms.09-0572
Variation of genes encoding GGPLs syntheses among Mycoplasma fermentans strains
Abstract
The information of the biosynthesis pathways of Mycoplasma fermentans specific major lipid-antigen, named glycoglycerophospholipids (GGPLs), is expected to be some of help to understand the virulence of M. fermentans. We examined primary structure of cholinephosphotransferase (mf1) and glucosyltransferase (mf3) genes, which engage GGPL-I and GGPL-III synthesis, in 20 strains, and found four types of variations in the mf1 gene but the mf3 gene in two strains was not detected by PCR. These results may have important implications in virulence factor of M. fermentans.
Similar articles
-
Enzymatic synthesis of Mycoplasma fermentans specific glycoglycerophospholipid from 1,2-dipalmitoylglycerol.J Biosci Bioeng. 2010 Apr;109(4):341-5. doi: 10.1016/j.jbiosc.2009.09.049. Epub 2009 Oct 24. J Biosci Bioeng. 2010. PMID: 20226374
-
Phosphocholine-containing glycoglycerolipids (GGPL-I and GGPL-III) are species-specific major immunodeterminants of Mycoplasma fermentans.Biochem Biophys Res Commun. 1997 Apr 28;233(3):644-9. doi: 10.1006/bbrc.1997.6443. Biochem Biophys Res Commun. 1997. PMID: 9168906
-
Molecular cloning and expression of a novel cholinephosphotransferase involved in glycoglycerophospholipid biosynthesis of Mycoplasma fermentans.Curr Microbiol. 2009 Jun;58(6):535-40. doi: 10.1007/s00284-009-9362-6. Epub 2009 Feb 14. Curr Microbiol. 2009. PMID: 19219498
-
"Unique choline-containing phosphoglycolipids in Mycoplasma fermentans".Chem Phys Lipids. 2016 Jan;194:94-100. doi: 10.1016/j.chemphyslip.2015.10.003. Epub 2015 Nov 10. Chem Phys Lipids. 2016. PMID: 26496149 Review. No abstract available.
-
Association of Mycoplasma fermentans and the risk of HIV-1 infection: A meta-analysis.Medicine (Baltimore). 2020 Jan;99(2):e18499. doi: 10.1097/MD.0000000000018499. Medicine (Baltimore). 2020. PMID: 31914019 Free PMC article.
Cited by
-
A sweeping view of avian mycoplasmas biology drawn from comparative genomic analyses.BMC Genomics. 2025 Jan 10;26(1):24. doi: 10.1186/s12864-024-11201-5. BMC Genomics. 2025. PMID: 39789465 Free PMC article.
-
An easy α-glycosylation methodology for the synthesis and stereochemistry of mycoplasma α-glycolipid antigens.Beilstein J Org Chem. 2012;8:629-39. doi: 10.3762/bjoc.8.70. Epub 2012 Apr 24. Beilstein J Org Chem. 2012. PMID: 22563361 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources