Measurement of the Velocity of Blood Flow (in vivo) Using a Fiber Optic Catheter and Optical Mixing Spectroscopy
- PMID: 20134853
- DOI: 10.1364/AO.14.000189
Measurement of the Velocity of Blood Flow (in vivo) Using a Fiber Optic Catheter and Optical Mixing Spectroscopy
Abstract
We have measured the velocity of blood flow in the femoral vein of a rabbit by detecting the Doppler shift of laser light introduced into the vein by means of a fiber optic catheter. A 0.5-mm diam optical monofiber inserted in the vein transmits both the incident light and collects the light scattered from the moving erythrocytes. The spectrum of heterodyne beat notes between the local oscillator, which originates at the end of the fiber, and the scattered light are measured using optical mixing spectroscopy.
Similar articles
-
In vivo Doppler shift measurements using multimode fiber-optic catheters.IEEE Trans Biomed Eng. 1998 Oct;45(10):1272-8. doi: 10.1109/10.720205. IEEE Trans Biomed Eng. 1998. PMID: 9775541
-
Relative blood velocity measurement in individual microvessels using the self-mixing effect in a fiber-coupled helium-neon laser.Microvasc Res. 1995 Mar;49(2):233-45. doi: 10.1006/mvre.1995.1019. Microvasc Res. 1995. PMID: 7603358
-
Fiber-coupled self-mixing diode-laser Doppler velocimeter: technical aspects and flow velocity profile disturbances in water and blood flows.Appl Opt. 1994 Aug 20;33(24):5628-41. doi: 10.1364/AO.33.005628. Appl Opt. 1994. PMID: 20935962
-
[2-dimensional mapping and retinal and papillary microcirculation using scanning laser Doppler flowmetry].Klin Monbl Augenheilkd. 1995 Sep;207(3):180-90. doi: 10.1055/s-2008-1035365. Klin Monbl Augenheilkd. 1995. PMID: 7474787 German.
-
Self-mixing feedback in a laser diode for intra-arterial optical blood velocimetry.Appl Opt. 2001 Sep 1;40(25):4608-15. doi: 10.1364/ao.40.004608. Appl Opt. 2001. PMID: 18360501
Cited by
-
Age-related cataracts: Role of unfolded protein response, Ca2+ mobilization, epigenetic DNA modifications, and loss of Nrf2/Keap1 dependent cytoprotection.Prog Retin Eye Res. 2017 Sep;60:1-19. doi: 10.1016/j.preteyeres.2017.08.003. Epub 2017 Aug 31. Prog Retin Eye Res. 2017. PMID: 28864287 Free PMC article. Review.
-
A laser Doppler catheter for monitoring both phasic and mean coronary vein flow.Heart Vessels. 1990;6(1):1-8. doi: 10.1007/BF02301875. Heart Vessels. 1990. PMID: 2149723
-
Spectrometer for laser-light scattering measurements of macromolecular and subcellular particle motions.Med Biol Eng Comput. 1982 Jan;20(1):37-43. doi: 10.1007/BF02441848. Med Biol Eng Comput. 1982. PMID: 7098556 No abstract available.
-
Single-fiber laser Doppler flowmetry. A method for deep tissue perfusion measurements.Med Biol Eng Comput. 1987 May;25(3):329-34. doi: 10.1007/BF02447433. Med Biol Eng Comput. 1987. PMID: 2966881 No abstract available.
-
Measurement of point velocity in the canine coronary artery by laser Doppler velocimeter with optical fiber.Jpn J Surg. 1981;11(4):226-31. doi: 10.1007/BF02468760. Jpn J Surg. 1981. PMID: 6457195
LinkOut - more resources
Other Literature Sources