Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2010 May;40(5):657-68; quiz 792-3.
doi: 10.1007/s00247-009-1503-3. Epub 2010 Feb 5.

Chronic granulomatous disease

Affiliations
Review

Chronic granulomatous disease

Alexander J Towbin et al. Pediatr Radiol. 2010 May.

Abstract

Chronic granulomatous disease (CGD) is a rare congenital immunodeficiency characterized by recurrent bacterial and fungal infections as well as granuloma formation. The manifestations of this disease can involve single or multiple organ systems. The lungs are the most commonly affected organ; however, lymphatic, hepatic, skeletal, gastrointestinal, genitourinary, head and neck, and central nervous system involvement have also been described. Most patients present with symptoms in their first few years of life. Due to the nonspecific manner in which patients present, the pediatric radiologist may be among the first to recognize the pattern of infection, inflammation, and granuloma formation leading to a diagnosis of CGD. The purpose of this paper is to review the imaging findings of CGD that can manifest throughout the body.

PubMed Disclaimer

References

    1. Medicine (Baltimore). 2000 May;79(3):155-69 - PubMed
    1. Radiographics. 2005 Sep-Oct;25(5):1183-95 - PubMed
    1. Clin Exp Immunol. 2008 May;152(2):211-8 - PubMed
    1. Eur Radiol. 2001;11(7):1259-62 - PubMed
    1. Colorectal Dis. 2006 Oct;8(8):637-44 - PubMed

LinkOut - more resources