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Review
. 2010 Apr 2;584(7):1280-6.
doi: 10.1016/j.febslet.2010.02.001. Epub 2010 Feb 5.

Current knowledge of the pre-autophagosomal structure (PAS)

Kuninori Suzuki  1 , Yoshinori Ohsumi
Affiliations
Free article
Review

Current knowledge of the pre-autophagosomal structure (PAS)

Kuninori Suzuki et al. FEBS Lett. .
Free article

Abstract

Autophagy is a system for degradation of bulk cellular components in lytic compartments, vacuoles, or lysosomes when eukaryotic cells face with nutrient starvation. In this review, we focus on the pre-autophagosomal structure (PAS), a functional entity responsible for autophagosome formation in Saccharomyces cerevisiae, and discuss its relevance to autophagy in mammalian cells.

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