Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1991 Jan 25;19(2):303-6.
doi: 10.1093/nar/19.2.303.

Polymorphisms generated by arbitrarily primed PCR in the mouse: application to strain identification and genetic mapping

J Welsh  1 , C Petersen, M McClelland
Affiliations
Free PMC article

Polymorphisms generated by arbitrarily primed PCR in the mouse: application to strain identification and genetic mapping

J Welsh et al. Nucleic Acids Res. .
Free PMC article

Abstract

Polymorphisms in genomic fingerprints generated by arbitrarily primed PCR (AP-PCR) can distinguish between strains of almost any organism. We applied the technique to the mouse (Mus musculus). The characteristic differences in the AP-PCR genomic fingerprints between strains will be of value in strain identification and verification. Using one primer, we genetically mapped four polymorphisms in a set of C57BL/6J x DBA/2J recombinant inbreds. One of these polymorphisms is a length variant. The method will allow rapid genetic mapping of DNA polymorphisms without Southern blotting.

PubMed Disclaimer

References

    1. Nature. 1978 Aug 24;274(5673):775-80 - PubMed
    1. Am J Hum Genet. 1980 May;32(3):314-31 - PubMed
    1. Nucleic Acids Res. 1982 Dec 11;10(23):7461-75 - PubMed
    1. Nucleic Acids Res. 1982 Dec 11;10(23):7865-77 - PubMed
    1. Nucleic Acids Res. 1983 Apr 11;11(7):2177-84 - PubMed

Publication types