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Comment
. 2010 Jan 22;140(2):174-6.
doi: 10.1016/j.cell.2010.01.014.

Blocking the deadly effects of the NMDA receptor in stroke

Henry G S Martin  1 , Yu Tian Wang
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Free article
Comment

Blocking the deadly effects of the NMDA receptor in stroke

Henry G S Martin et al. Cell. .
Free article

Abstract

Excessive activation of NMDA glutamate receptors contributes to neuronal death after stroke. In this issue, Tu et al. (2010) demonstrate that ischemic injury promotes the association of death-associated protein kinase 1 with the NMDA receptor, thereby potentiating its activity, and show that disrupting this association reduces damage to the brain.

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