The brothers RAF
- PMID: 20141832
- DOI: 10.1016/j.cell.2010.01.013
The brothers RAF
Abstract
Targeted molecular therapies for cancer treatment have shown promise, but also have limitations. In this issue, Heidorn et al. (2010) find that a class of targeted molecular therapies with clinical effectiveness against one melanoma subtype may have adverse clinical effects in another.
Copyright 2010 Elsevier Inc. All rights reserved.
Comment on
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Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF.Cell. 2010 Jan 22;140(2):209-21. doi: 10.1016/j.cell.2009.12.040. Cell. 2010. PMID: 20141835 Free PMC article.
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