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doi: 10.1016/j.cell.2010.01.035.
Shedding light on sperm pHertility
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- PMID: 20144756
- DOI: 10.1016/j.cell.2010.01.035
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Comment
Shedding light on sperm pHertility
Cell.
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Abstract
The acquisition of fertilization capacity by sperm is regulated by intracellular pH (pH(i)), but the transport pathways that regulate pH(i) are not well understood. Lishko et al. (2010) now report that Hv1, the voltage-sensitive proton channel, is present in human sperm and is an important regulator of the functional maturation of sperm.
2010 Elsevier Inc. All rights reserved.
Comment on
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Acid extrusion from human spermatozoa is mediated by flagellar voltage-gated proton channel.Cell. 2010 Feb 5;140(3):327-37. doi: 10.1016/j.cell.2009.12.053. Cell. 2010. PMID: 20144758
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