NO Signals from the Cancer Stem Cell Niche
- PMID: 20144782
- DOI: 10.1016/j.stem.2010.01.007
NO Signals from the Cancer Stem Cell Niche
Abstract
Characterization of signaling pathways that control cancer stem cells may lead to more effective treatments against cancer. In this issue of Cell Stem Cell, a study by Charles et al. (2010) identifies the NO and Notch pathways as important regulators of the perivascular niche of cancer stem cells in glioma.
Copyright 2010 Elsevier Inc. All rights reserved.
Comment on
-
Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells.Cell Stem Cell. 2010 Feb 5;6(2):141-52. doi: 10.1016/j.stem.2010.01.001. Cell Stem Cell. 2010. PMID: 20144787 Free PMC article.
Similar articles
-
Insulin signals control the competence of the Drosophila female germline stem cell niche to respond to Notch ligands.Dev Biol. 2011 Feb 15;350(2):290-300. doi: 10.1016/j.ydbio.2010.11.032. Epub 2010 Dec 8. Dev Biol. 2011. PMID: 21145317
-
FOXO/Fringe is necessary for maintenance of the germline stem cell niche in response to insulin insufficiency.Dev Biol. 2013 Oct 1;382(1):124-35. doi: 10.1016/j.ydbio.2013.07.018. Epub 2013 Jul 27. Dev Biol. 2013. PMID: 23895933
-
Maturation of tumor vasculature by interferon-beta disrupts the vascular niche of glioma stem cells.Anticancer Res. 2010 Sep;30(9):3301-8. Anticancer Res. 2010. PMID: 20944101
-
How the niche regulates hematopoietic stem cells.Chem Biol Interact. 2010 Mar 19;184(1-2):7-15. doi: 10.1016/j.cbi.2009.11.012. Epub 2009 Nov 26. Chem Biol Interact. 2010. PMID: 19944675 Review.
-
Normal stem cells and cancer stem cells: the niche matters.Cancer Res. 2006 May 1;66(9):4553-7. doi: 10.1158/0008-5472.CAN-05-3986. Cancer Res. 2006. PMID: 16651403 Review.
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources