NO Signals from the Cancer Stem Cell Niche
- PMID: 20144782
- DOI: 10.1016/j.stem.2010.01.007
NO Signals from the Cancer Stem Cell Niche
Abstract
Characterization of signaling pathways that control cancer stem cells may lead to more effective treatments against cancer. In this issue of Cell Stem Cell, a study by Charles et al. (2010) identifies the NO and Notch pathways as important regulators of the perivascular niche of cancer stem cells in glioma.
Copyright 2010 Elsevier Inc. All rights reserved.
Comment on
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Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells.Cell Stem Cell. 2010 Feb 5;6(2):141-52. doi: 10.1016/j.stem.2010.01.001. Cell Stem Cell. 2010. PMID: 20144787 Free PMC article.
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