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Comment
. 2010 Feb 15;16(4):1085-7.
doi: 10.1158/1078-0432.CCR-09-3246. Epub 2010 Feb 9.

Finding the right dose for cancer therapeutics--can we do better?

Eric H Rubin  1 , Keaven M Anderson
Affiliations
Comment

Finding the right dose for cancer therapeutics--can we do better?

Eric H Rubin et al. Clin Cancer Res. .

Abstract

Unlike other diseases, dose-selection for cancer therapeutics is often based on the maximum-tolerated dose in phase 1 studies involving relatively few patients. In this issue of Clinical Cancer Research, Jain and colleagues provide evidence that lower doses may be as effective as maximum-tolerated doses in the treatment of cancer patients.

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