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. 2010 Mar 2;102(5):930-2.
doi: 10.1038/sj.bjc.6605556. Epub 2010 Feb 9.

Distribution of HPV types associated with cervical cancers in Scotland and implications for the impact of HPV vaccines

K Cuschieri  1 , D H Brewster, A R W Williams, D Millan, G Murray, S Nicoll, J Imrie, A Hardie, C Graham, H A Cubie
Affiliations

Distribution of HPV types associated with cervical cancers in Scotland and implications for the impact of HPV vaccines

K Cuschieri et al. Br J Cancer. .

Abstract

Background/methods: This study evaluated human papillomavirus (HPV) type prevalence in 370 Scottish invasive cervical cancers (ICCs) using HPV genotyping and HPV mRNA detection.

Results: HPV 16 and/or 18 was detected in 72% of cancers overall and in 82% of HPV-positive cancers. HPV 45 and 16 were the most frequently transcribed types.

Conclusion: A significant reduction in ICC in Scotland should be achieved through the HPV immunisation programme.

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