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Review
. 2010 Aug;62(2):144-9.
doi: 10.1016/j.phrs.2010.01.014. Epub 2010 Feb 10.

Magnetic nanoparticles and targeted drug delivering

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Review

Magnetic nanoparticles and targeted drug delivering

Jana Chomoucka et al. Pharmacol Res. 2010 Aug.

Abstract

Magnetic nanoparticles (MNPs) are being of great interest due to their unique purposes. Especially in medicine, application of MNPs is much promising. MNPs have been actively investigated as the next generation of targeted drug delivery for more than thirty years. The importance of targeted drug delivery and targeted drug therapy is to transport a drug directly to the centre of the disease under various conditions and thereby treat it deliberately, with no effects on the body. Usage of MNPs depends largely on the preparation processes to select optimal conditions and election agents to modify their surface. This review summarizes the most commonly used functionalization methods of the MNPs preparation methods and their use in targeted drug delivery and targeted therapy.

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