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Comment

. 2010 Feb 12;327(5967):791-2.

doi: 10.1126/science.1187155.

Genetics. Genetic control of hotspots

Vivian G Cheung¹, Stephanie L Sherman, Eleanor Feingold

Affiliations

PMID: 20150474
DOI: 10.1126/science.1187155

Comment

Genetics. Genetic control of hotspots

Vivian G Cheung et al. Science. 2010.

. 2010 Feb 12;327(5967):791-2.

doi: 10.1126/science.1187155.

Authors

Vivian G Cheung¹, Stephanie L Sherman, Eleanor Feingold

Affiliation

¹ Howard Hughes Medical Institute, Department of Pediatrics, University of Pennsylvania, Philadelphia, PA 19104, USA. vcheung@mail.med.upenn.edu

PMID: 20150474
DOI: 10.1126/science.1187155

No abstract available

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Comment on

Prdm9 controls activation of mammalian recombination hotspots.
Parvanov ED, Petkov PM, Paigen K. Parvanov ED, et al. Science. 2010 Feb 12;327(5967):835. doi: 10.1126/science.1181495. Epub 2009 Dec 31. Science. 2010. PMID: 20044538 Free PMC article.
PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice.
Baudat F, Buard J, Grey C, Fledel-Alon A, Ober C, Przeworski M, Coop G, de Massy B. Baudat F, et al. Science. 2010 Feb 12;327(5967):836-40. doi: 10.1126/science.1183439. Epub 2009 Dec 31. Science. 2010. PMID: 20044539 Free PMC article.
Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination.
Myers S, Bowden R, Tumian A, Bontrop RE, Freeman C, MacFie TS, McVean G, Donnelly P. Myers S, et al. Science. 2010 Feb 12;327(5967):876-9. doi: 10.1126/science.1182363. Epub 2009 Dec 31. Science. 2010. PMID: 20044541 Free PMC article.

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