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. 2010 Jun;17(6):1669-74.
doi: 10.1245/s10434-010-0957-8. Epub 2010 Feb 12.

Skin-sparing mastectomy and immediate breast reconstruction in the management of locally recurrent breast cancer

A J Lindford  1 , T J Meretoja, K A J von Smitten, T A Jahkola
Affiliations

Skin-sparing mastectomy and immediate breast reconstruction in the management of locally recurrent breast cancer

A J Lindford et al. Ann Surg Oncol. 2010 Jun.

Abstract

Aim: To investigate whether skin-sparing mastectomy (SSM) and immediate breast reconstruction (IBR) is a possible treatment option in selected cases of locally recurrent breast cancer after previous breast-conserving therapy (BCT).

Material and methods: Sixty consecutive patients were treated by SSM and IBR between 1995 and 2008 for ipsilateral breast tumour recurrence (IBTR). Selection criteria consisted of: IBTR <3 cm size, not infiltrating skin or chest wall, primarily node negative, recurrence >3 years after primary operation, and no metastases. Patient records were analysed retrospectively and follow-up data on patient outcome included.

Results: The reconstruction method consisted of 40 free abdominal flaps, 18 latissimus dorsi (LD) flaps with or without an implant, and two cases of implant only. Twenty-three patients received adjuvant oncological therapy. During median follow-up of 66 months, 11 patients (18%) developed disease relapse, including 6 (10%) local re-recurrences.

Conclusion: IBR is a possible treatment option for patients who develop local recurrence following earlier BCT. Our local re-recurrence rate of 10% compares well with that following salvage mastectomy for IBTR. Of patients, 43% did not actually meet our selection criteria but yet appeared to fare well in terms of outcome. Therefore we should re-evaluate our selection criteria.

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