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Review
. 2010 Feb;7(2):245-58.
doi: 10.1002/cbdv.200900281.

The resurgence of acyclic nucleic acids

Su Zhang  1 , Christopher Switzer, John C Chaput
Affiliations
Review

The resurgence of acyclic nucleic acids

Su Zhang et al. Chem Biodivers. 2010 Feb.

Abstract

This review examines acyclic nucleoside analogs as therapeutic agents, potential progenitor candidates to RNA, and novel building blocks for nucleic-acid nanotechnology. Together, these areas of research provide new insights into the structural and functional properties of nucleic acids and suggest new paradigms for nucleic acid self-assembly.

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