Review
doi: 10.1016/j.neuron.2010.01.015.
Kalzium ist nicht alles
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- PMID: 20152120
- DOI: 10.1016/j.neuron.2010.01.015
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Review
Kalzium ist nicht alles
Neuron.
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Abstract
Elevation of cerebral Mg2+ with a novel orally delivered ionophore, magnesium threonate, enhances cognition in young and old rats over a 12-24 day treatment interval, as outlined in a paper by Slutsky et al. in this issue of Neuron. Despite both Mg2+ and Zn2+ blocking the NMDA receptor channel, sustained extracellular Mg2+ elevation mimics sustained synaptic Zn2+ concentrations by increasing hippocampal NR2B expression and bouton density.
Copyright 2010 Elsevier Inc. All rights reserved.
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Enhancement of learning and memory by elevating brain magnesium.Neuron. 2010 Jan 28;65(2):165-77. doi: 10.1016/j.neuron.2009.12.026. Neuron. 2010. PMID: 20152124
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