Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2010 Jan 12;20(1):R13-5.
doi: 10.1016/j.cub.2009.11.018.

Host-pathogen interactions: proline gives insect pathogens the green light

Nick Waterfield  1
Affiliations
Free article
Comment

Host-pathogen interactions: proline gives insect pathogens the green light

Nick Waterfield. Curr Biol. .
Free article

Abstract

How does a quiescent symbiont of a nematode worm know when to turn nasty? Metabolic analysis and genetic knockouts confirm that model insect pathogens can sense L-proline in insect blood. This not only serves as a wake-up call, activating secondary metabolite virulence factors, but also provides an energy source for a metabolic shift appropriate for adaptation to the host environment.

PubMed Disclaimer

Comment on

LinkOut - more resources