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Comment
. 2010 Jan 19;18(1):6-7.
doi: 10.1016/j.devcel.2010.01.001.

Dcr1 tracked down

Lucas J T Kaaij  1 , René F Ketting
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Dcr1 tracked down

Lucas J T Kaaij et al. Dev Cell. .
Free article

Abstract

RNAi is essential for pericentromeric heterochromatic formation in S. pombe, and although Dcr1, the initiator protein of this process, has been biochemically well described, its subcellular localization has remained elusive. In this issue of Developmental Cell, Emmerth et al. now show that Dcr1 is dynamically shuttling between nucleus and cytoplasm, adding new insight into the subcellular mechanics of RNAi.

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