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Case Reports
. 2010 Jul-Aug;53(4):225-6.
doi: 10.1016/j.ejmg.2010.02.001. Epub 2010 Feb 10.

Synophrys

Matthias Möhrenschlager  1 , Martin Lauenstein, Johannes Ring, Claudia Steiner
Affiliations
Case Reports

Synophrys

Matthias Möhrenschlager et al. Eur J Med Genet. 2010 Jul-Aug.

Abstract

Introduction: Meeting of the medial eyebrows in the midline (synophrys) may serve as a cutaneous marker lesion for syndromal disorders (e.g. Cornelia de Lange syndrome).

Case presentation: A 31-year-old man showed supercilia forming a single band of terminal hairs between left and right lateral orbital rim. Medical examination of the patient revealed coldness-inducable urticaria, xanthelasma formation and long eyelashes without any signs of a syndromal disorder.

Conclusion: Synophrys can be found in some syndromal disorders, but are not pathognomonic for any illness per se.

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