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Review
. 2010 Jun 15;62(7-8):753-64.
doi: 10.1016/j.addr.2010.02.003. Epub 2010 Feb 11.

Scaffold-free cell delivery for use in regenerative medicine

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Review

Scaffold-free cell delivery for use in regenerative medicine

Jens M Kelm et al. Adv Drug Deliv Rev. .

Abstract

The development of cell-based therapies for diseased tissues is one of the most promising research directions in regenerative medicine. Cell-delivery methods are an essential part of cell therapy concepts. Therapies with the potential to become clinical routine will only be possible if these methods ensure efficient engraftment and therapeutically-relevant number of cells survive. Here we provide an overview of three different scaffold-free cell-delivery concepts: (i) single cell delivery, (ii) cell sheet engineering and (iii) microtissue technology.

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