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. 2009 Dec 7;14 Suppl 4(Suppl 4):101-3.
doi: 10.1186/2047-783x-14-s4-101.

Cardiac autonomic control in adolescents with primary hypertension

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Cardiac autonomic control in adolescents with primary hypertension

Z Havlicekova et al. Eur J Med Res. .

Abstract

Background: Impairment in cardiovascular autonomic regulation participates in the onset and maintenance of primary hypertension.

Objective: The aim of the present study was to evaluate cardiac autonomic control using long-term heart rate variability (HRV) analysis in adolescents with primary hypertension.

Subjects and methods: Twenty two adolescent patients with primary hypertension (5 girls/17 boys) aged 14-19 years and 22 healthy subjects matched for age and gender were enrolled. Two periods from 24-hour ECG recording were evaluated by HRV analysis: awake state and sleep. HRV analysis included spectral power in low frequency band (LF), in high frequency band (HF), and LF/HF ratio. -

Results: In awake state, adolescents with primary hypertension had lower HF and higher LF and LF/HF ratio. During sleep, HF was lower and LF/HF ratio was higher in patients with primary hypertension.

Conclusions: A combination of sympathetic predominance and reduced vagal activity might represent a potential link between psychosocial factors and primary hypertension, associated with increased cardiovascular morbidity.

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