Cardiac autonomic control in adolescents with primary hypertension
- PMID: 20156736
- PMCID: PMC3521333
- DOI: 10.1186/2047-783x-14-s4-101
Cardiac autonomic control in adolescents with primary hypertension
Abstract
Background: Impairment in cardiovascular autonomic regulation participates in the onset and maintenance of primary hypertension.
Objective: The aim of the present study was to evaluate cardiac autonomic control using long-term heart rate variability (HRV) analysis in adolescents with primary hypertension.
Subjects and methods: Twenty two adolescent patients with primary hypertension (5 girls/17 boys) aged 14-19 years and 22 healthy subjects matched for age and gender were enrolled. Two periods from 24-hour ECG recording were evaluated by HRV analysis: awake state and sleep. HRV analysis included spectral power in low frequency band (LF), in high frequency band (HF), and LF/HF ratio. -
Results: In awake state, adolescents with primary hypertension had lower HF and higher LF and LF/HF ratio. During sleep, HF was lower and LF/HF ratio was higher in patients with primary hypertension.
Conclusions: A combination of sympathetic predominance and reduced vagal activity might represent a potential link between psychosocial factors and primary hypertension, associated with increased cardiovascular morbidity.
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