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Comment

. 2009 Apr 13;1(4):350-3.

doi: 10.18632/aging.100039.

A role for cyclooxygenase-1 in beta-amyloid-induced neuroinflammation

Eduardo Candelario-Jalil¹

Affiliations

PMID: 20157521
PMCID: PMC2806016
DOI: 10.18632/aging.100039

Comment

A role for cyclooxygenase-1 in beta-amyloid-induced neuroinflammation

Eduardo Candelario-Jalil. Aging (Albany NY). 2009.

. 2009 Apr 13;1(4):350-3.

doi: 10.18632/aging.100039.

Author

Eduardo Candelario-Jalil¹

Affiliation

¹ Department of Neurology, University of New Mexico, Health Sciences Center MSC10 5620, Albuquerque, NM 87131-0001, USA. ECandelario-Jalil@salud.unm.edu

PMID: 20157521
PMCID: PMC2806016
DOI: 10.18632/aging.100039

No abstract available

Keywords: Alzheimer's disease; COX-1; COX-2; microglia; neuroinflammation; oxidative stress; β-amyloid.

PubMed Disclaimer

Conflict of interest statement

The author of this manuscript has no conflict of interests to declare.

Comment on

Cyclooxygenase-1 null mice show reduced neuroinflammation in response to beta-amyloid.
Choi SH, Bosetti F. Choi SH, et al. Aging (Albany NY). 2009 Feb 11;1(2):234-44. doi: 10.18632/aging.100021. Aging (Albany NY). 2009. PMID: 20157512 Free PMC article.

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References

1. Boche D, Nicoll JA. The role of the immune system in clearance of Abeta from the brain. Brain Pathol. 2008;18:267–278. - PMC - PubMed
1. McGeer PL, Schulzer M, McGeer EG. Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies. Neurology. 1996;47:425–432. - PubMed
1. in t' Veld BA, Ruitenberg A, Hofman A, Launer LJ, van Duijn CM, Stijnen T, Breteler MM, Stricker BH. Nonsteroidal antiinflammatory drugs and the risk of Alzheimer's disease. N Engl J Med. 2001;345:1515–1521. - PubMed
1. McGeer PL, McGeer EG. NSAIDs and Alzheimer disease: epidemiological, animal model and clinical studies. Neurobiol Aging. 2007;28:639–647. - PubMed
1. Hoozemans JJ, Rozemuller JM, van Haastert ES, Veerhuis R, Eikelenboom P. Cyclooxygenase-1 and -2 in the different stages of Alzheimer's disease pathology. Curr Pharm Des. 2008;14:1419–1427. - PubMed

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