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Review
. 2010 Mar;33(1):141-58.
doi: 10.1016/j.psc.2009.11.001.

Genetics of obsessive-compulsive disorder

Gerald Nestadt  1 , Marco Grados, Jack F Samuels
Affiliations
Review

Genetics of obsessive-compulsive disorder

Gerald Nestadt et al. Psychiatr Clin North Am. 2010 Mar.

Abstract

Obsessive-compulsive disorder is a common debilitating condition affecting individuals from childhood through adult life. There is good evidence of genetic contribution to its etiology, but environmental risk factors also are likely to be involved. The condition probably has a complex pattern of inheritance. Molecular studies have identified several potentially relevant genes, but much additional research is needed to establish definitive causes of the condition.

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Figures

Figure 1
Figure 1
Results of association studies of SLC1A1 in OCD.
Figure 2
Figure 2
Linkage results from the OCGS.
See this image and copyright information in PMC

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