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Comment
. 2010 Feb 10;18(2):149-51.
doi: 10.1016/j.str.2010.01.007.

Werner helicase wings DNA binding

Kelly A Hoadley, James L Keck
Comment

Werner helicase wings DNA binding

Kelly A Hoadley et al. Structure. .

Abstract

In this issue of Structure, Kitano et al. describe the structure of the DNA-bound winged-helix domain from the Werner helicase. This structure of a RecQ/DNA complex offers insights into the DNA-unwinding mechanisms of RecQ family helicases.

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Figures

Figure 1
Figure 1
Comparison of RecQ helicases. A. The WRN WH/DNA complex (blue) is shown overlaid with human RecQ1 catalytic core (orange, left), and with E. coli RecQ catalytic core (tan, right). B. Close-up showing the β-wing and important residues.
See this image and copyright information in PMC

Comment on

References

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