Comment
doi: 10.1016/j.molcel.2010.01.027.
The fast track to multidrug resistance
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- PMID: 20159549
- DOI: 10.1016/j.molcel.2010.01.027
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Comment
The fast track to multidrug resistance
Mol Cell.
.
Free article
Abstract
In this issue of Molecular Cell, Kohanski et al. (2010) demonstrate that even subinhibitory concentrations of bactericidal antibiotics result in the generation of reactive oxygen species, leading to an increase in mutation rate and the emergence of multidrug-resistant bacterial strains.
Comment on
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Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis.Mol Cell. 2010 Feb 12;37(3):311-20. doi: 10.1016/j.molcel.2010.01.003. Mol Cell. 2010. PMID: 20159551 Free PMC article.
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