Comment
doi: 10.1016/j.devcel.2010.02.002.
Telomeric TuRF1 wars
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- PMID: 20159586
- DOI: 10.1016/j.devcel.2010.02.002
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Comment
Telomeric TuRF1 wars
Dev Cell.
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Free article
Abstract
The TRF1 subunit of the shelterin complex controls telomere length by regulating telomerase access to chromosome ends. Work from Zeng et al. (2010) now reveals in atomic detail how a battle between the SCF(FBX4) ubiquitin ligase and the shelterin component TIN2 controls TRF1 abundance and telomere length homeostasis.
Copyright (c) 2010 Elsevier Inc. All rights reserved.
Comment on
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Structural basis of selective ubiquitination of TRF1 by SCFFbx4.Dev Cell. 2010 Feb 16;18(2):214-25. doi: 10.1016/j.devcel.2010.01.007. Dev Cell. 2010. PMID: 20159592 Free PMC article.
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