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. 2009 Aug 12;50(32):4571-4574.
doi: 10.1016/j.tetlet.2009.05.067.

Euryjanicin A: a new cycloheptapeptide from the Caribbean marine sponge Prosuberites laughlini

Jan Vicente  1 , Brunilda Vera, Abimael D Rodríguez, Idaliz Rodríguez-Escudero, Raphael G Raptis
Affiliations

Euryjanicin A: a new cycloheptapeptide from the Caribbean marine sponge Prosuberites laughlini

Jan Vicente et al. Tetrahedron Lett. .

Abstract

A new proline-containing cycloheptapeptide, euryjanicin A (1), has been isolated from the marine sponge Prosuberites laughlini indigenous to Puerto Rico, and its structure established by an X-ray crystal structure determination. The absolute configuration of each amino acid residue was determined by Marfey's method.

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Figures

Figure 1
Figure 1
1H (500 MHz) (A) and 13C (125 MHz) (B) NMR spectra of euryjanicin A (1) in CDCl3 at 25 °C. The doubling and tripling of resonances observed in the NMR spectra is attributed to the existence of slow conformational equilibria.
Figure 2
Figure 2
Perspective drawing of the X-ray crystal structure of euryjanicin A (1). Hydrogen atoms have been omitted for clarity and selected atoms are labeled. Carbon atoms are indicated in black, nitrogens in blue, and oxygens in red.
See this image and copyright information in PMC

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