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. 2009 Mar 1;4(1):37-46.
doi: 10.1016/j.jsmc.2008.11.003.

Rationale, design and findings from the Wisconsin Sleep Cohort Study: Toward understanding the total societal burden of sleep disordered breathing

Terry Young  1
Affiliations

Rationale, design and findings from the Wisconsin Sleep Cohort Study: Toward understanding the total societal burden of sleep disordered breathing

Terry Young. Sleep Med Clin. .
No abstract available

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Figures

Figure 1
Figure 1. The Total Public Burden of SDB is a function of

  1. The number of cases of SDB (prevalence), multiplied by

  2. The costs of SDB, including:

    1. direct costs

      1. monentary cost of diagnosis and treatment,

      2. distress, discomfort associated with having SDB to the individual sufferer, including unsatisfactory sleep, low motivation, problems with daytime functioning, quality of life, relationships, etc,

      3. loss to family and society (loss of potential contributions to community e.g., jobs, volunteer sevices)

      4. morbidity attributable to SDB (e.g., hypertension, depression)

      5. loss of years of life attributable to SDB

    2. indirect costs

      1. SDB exacerbation of comorbidity

      2. worse prognosis for other disorders due to SDB-related behavioral morbidity (e.g., low compliance with therapy for other disorders, lack of exercise)

  3. Modifying factors

    1. prevention programs to reduce prevalence and progression of SDB (e.g., weight loss)

    2. increases in factors that cause or worse SDB (e.g., ongoing obesity epidemic, aging of the popuation)

    3. treatment of SDB that prevents or reduces adverse outcomes

Figure 2
Figure 2
Selection biases for clinical recognition and diagnosis of sleep apnea. The proportion of all cases of sleep apnea is represented by the iceberg, with clinically diagnosed cases shown in the tip of the iceberg. Clinically recognized sleep apnea represents less than 85% of the total prevalence of sleep apnea cases that would be candidates fo treatment. Factors that favor selection of individuals with unrecognized sleep apnea (below the tip of the iceberg) for clinical referral and diagnosis are shown.
Figure 3
Figure 3
Wisconsin Sleep Cohort Study Design and Protocol A two-stage sampling design was used to obtain the WSCS sample for baseline and 4-year follow-up overnight protocols. The basic study protocol is listed.
Figure 3
Figure 3
Wisconsin Sleep Cohort Study Design and Protocol A two-stage sampling design was used to obtain the WSCS sample for baseline and 4-year follow-up overnight protocols. The basic study protocol is listed.
See this image and copyright information in PMC

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