doi: 10.4314/ajtcam.v5i1.31252.
Analgesic and anti-inflammatory activities of Asparagus africanus root extract
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- PMID: 20162051
- PMCID: PMC2816601
- DOI: 10.4314/ajtcam.v5i1.31252
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Analgesic and anti-inflammatory activities of Asparagus africanus root extract
Afr J Tradit Complement Altern Med.
.
Abstract
The methanolic extract of the roots of Asparagus africanus Lam (Liliaceae) which contains mainly saponins and carbohydrate showed significant analgesic and anti-inflammatory activities (P<0.05) in the tail-flick/hot-plate test and egg albumen-induced rat paw oedema tests that were comparable to the test drugs (morphine 20 mg/kg and indomethacin 50 mg/kg respectively). These results indicate that the extract possesses analgesic and anti-inflammatory properties.
Keywords: Asparagus africanus; analgesic and anti-inflammatory activities; roots.
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References
-
- Berbera RJ, Trovato AJ, Repisarda A, Requsa S. Analgesic and Anti-inflammatory Activity in Acute and Chronic Conditions of Trema guineense (Schum. et Thonn) Ficalhu and Trema micantha Blume Extracts in Rodents. Phytother Res. 1992;6:144–146.
-
- Collier HOJ. Analgesic. In: Laurence DR, Bacharach AL, editors. Evaluation of Drug Activities: Pharmacometric. Vol. 1. London and New York: Academic Press; 1964. pp. 183–203.
-
- Dalziel JM. The Useful Plants of West Tropical Africa. London: Crown Agents for Overseas Government and Administration; 1956. p. 477.
-
- Debella AJ, Hasliger EJ, Kunert OJ, Michl G, Abebe D. Steroidal Saponins from Asparagus africanus. Phytochemistry. 1999;5(8):1069–1075. - PubMed
-
- Desta B. Ethiopian traditional herbal drugs, part II. Antimicrobial activity of 63 mechanical plants. J Ethnopharmacol. 1993;39(2):129–139. - PubMed
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