Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2010 Jul 1;54(7):1045-7.
doi: 10.1002/pbc.22434.

Orbital sarcoma with metastases at diagnosis: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group

Winston W Huh  1 , James R Anderson, David Rodeberg, Lisa Teot, Torunn Yock, R Beverly Raney
Affiliations
Case Reports

Orbital sarcoma with metastases at diagnosis: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group

Winston W Huh et al. Pediatr Blood Cancer. .

Abstract

We reviewed clinicopathologic features and treatment outcomes in seven patients diagnosed with Stage 4/Group IV orbital sarcoma and treated on IRSG protocols I-III. Three patients had embryonal rhabdomyosarcoma (RMS), and two patients each had alveolar RMS or unclassified sarcoma. Median age at diagnosis was 1.8 years (range 0.2-6.9 years). All patients had bone marrow involvement, including six with normal complete blood count at diagnosis. Cerebrospinal fluid was normal in six patients. Three patients survived >5 years, including one with local recurrence. In conclusion, further study is needed to determine necessity of bone marrow and CSF examination in orbital sarcoma patients.

PubMed Disclaimer

References

    1. Arndt CAS, Crist WM. Common musculoskeletal tumors of childhood and adolescence. N Engl J Med. 1999;341:342–352. - PubMed
    1. Oberlin O, Rey A, Anderson J, et al. Treatment of orbital rhabdomyosarcoma: survival and late effects of treatment – results of an international workshop. J Clin Oncol. 2001;19:197–204. - PubMed
    1. Maurer H, Beltangady M, Gehan E, et al. The Intergroup Rhabdomyosarcoma Study – I: a final report. Cancer. 1988;61:209–220. - PubMed
    1. Maurer H, Gehan E, Beltangady M, et al. The Intergroup Rhabdomyosarcoma Study – II. Cancer. 1993;71:1904–1922. - PubMed
    1. Crist W, Gehan EA, Ragab AH, et al. The third Intergroup Rhabdomyosarcoma Study. J Clin Oncol. 1995;13:610–630. - PubMed

Publication types

MeSH terms