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Randomized Controlled Trial
. 2010 Mar-Apr;19(2):111-8.
doi: 10.1111/j.1521-0391.2009.00015.x.

The relationship between depression and smoking cessation outcomes in treatment-seeking substance abusers

Susan C Sonne  1 , Edward V Nunes, Huiping Jiang, Clare Tyson, John Rotrosen, Malcolm S Reid
Affiliations
Randomized Controlled Trial

The relationship between depression and smoking cessation outcomes in treatment-seeking substance abusers

Susan C Sonne et al. Am J Addict. 2010 Mar-Apr.

Abstract

The National Drug Abuse Treatment Clinical Trials Network (CTN) recently completed a randomized, open label trial comparing treatment as usual (TAU) combined with nicotine patches plus cognitive behavioral group counseling for smoking cessation (n = 153) to TAU alone (n = 72) for patients enrolled in treatment programs for drug or alcohol dependence, who were interested in quitting smoking. This report is a secondary analysis evaluating the effect of depressive symptomatology (n = 70) or history of depression (n = 110) on smoking cessation outcomes. A significant association was seen between measures of depression and difficulty quitting cigarettes. Specifically, there was a greater probability for smoking abstinence for those with lower baseline Beck Depression Inventory II (BDI-II) scores. These data suggest that evaluation and treatment of depressive symptoms may play an important role in improving smoking cessation outcomes. (Am J Addict 2010;00:1-8).

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Figures

Figure 1
Figure 1
Smoking Abstinence by Baseline BDI
Figure 2
Figure 2
Expired CO by baseline BDI
Figure 3
Figure 3
Nicotine withdrawal by baseline BDI
See this image and copyright information in PMC

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