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Randomized Controlled Trial
. 2010 May;21(5):529-34.
doi: 10.1007/s00192-009-1018-3. Epub 2010 Feb 18.

Porcine skin collagen implants for anterior vaginal wall prolapse: a randomised prospective controlled study

Ulla Hviid  1 , Thomas Vauvert F Hviid, Martin Rudnicki
Affiliations
Randomized Controlled Trial

Porcine skin collagen implants for anterior vaginal wall prolapse: a randomised prospective controlled study

Ulla Hviid et al. Int Urogynecol J. 2010 May.

Abstract

Introduction and hypothesis: The effect of a Pelvicol graft compared with a conventional anterior vaginal repair was evaluated in this randomised controlled study.

Methods: Only patients with a stage II or higher (Ba >or= -1) defect were included.

Results: Thirty-one patients were allocated to a conventional anterior repair; 30 to Pelvicol graft. At 12 months follow-up, four patients among controls (15%) and two in the graft group (7%) had objective recurrence. Among controls, the difference at 3 months follow-up in Ba was 6.0 cm when compared with the position of Ba prior to surgery. In the graft group, the difference was 7.0 cm (P < 0.05). This difference was still present at 12 months follow-up (6.0 vs. 7.0 cm; P < 0.05).

Conclusions: The implantation of a Pelvicol graft does not improve the POP-Q stage.

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