Stomach dysfunction in diabetes mellitus: emerging technology and pharmacology
- PMID: 20167183
- PMCID: PMC2825640
- DOI: 10.1177/193229681000400123
Stomach dysfunction in diabetes mellitus: emerging technology and pharmacology
Abstract
Gastroparesis and other types of gastric dysfunction result in substantial morbidity in diabetes patients. The pathophysiology of these disorders is incompletely understood. This article reviews techniques applicable to the assessment of gastric function in diabetes patients, including the measurement of emptying, accommodation, and contractility. Available treatment options are also reviewed, including novel yet unapproved serotonin 5-HT(4) agonist pharmacological treatments, as well as the role of endoscopic, surgical, and device treatments of gastroparesis.
2010 Diabetes Technology Society.
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References
-
- Soykan I, Sivri B, Sarosiek I, Kiernan B, McCallum RW. Demography, clinical characteristics, psychological and abuse profiles, treatment, and long-term follow-up of patients with gastroparesis. Dig Dis Sci. 1998;43(11):2398–2404. - PubMed
-
- Hoogerwerf WA, Pasricha PJ, Kalloo AN, Schuster MM. Pathe overlooked symptom in gastroparesis. Am J Gastroenterol. 1999;94(4):1029–1033. - PubMed
-
- Jones KL, Russo A, Stevens JE, Wishart JM, Berry MK, Horowitz M. Predictors of delayed gastric emptying in diabetes. Diabetes Care. 2001;24(7):1264–1269. - PubMed
-
- Delgado-Aros S, Camilleri M, Castillo EJ, Cremonini F, Stephens D, Ferber I, Baxter K, Burton D, Zinsmeister AR. Effect of gastric volume or emptying on meal-related symptoms after liquid nutrients in obesity: a pharmacologic study. Clin Gastroenterol Hepatol. 2005;3(10):997–1006. - PubMed
-
- Delgado-Aros S, Camilleri M, Cremonini F, Ferber I, Stephens D, Burton DD. Contributions of gastric volumes and gastric emptying to meal size and postmeal symptoms in functional dyspepsia. Gastroenterology. 2004;127(6):1685–1694. - PubMed