Review
[Pathogenesis of posterior capsule opacification in pseudophakia]
[Article in
Polish]
Affiliations
- PMID: 20169899
Item in Clipboard
Review
[Pathogenesis of posterior capsule opacification in pseudophakia]
[Article in
Polish]
Klin Oczna.
2009.
Abstract
The lens epithelial cells of A and E type are involved in pathogenesis of posterior capsule opacification (PCO). They undergo metaplasia into microfibroblasts, then migrate towards posterior capsule where they proliferate and form opacification. These processes are stimulated by cytokines and interleukines. The extracellular matrix which constitutes a scaffold for migration and attachment of epithelial cells plays an important role in PCO formation. Integrines intercede in this process.
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