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Review
. 2010 Mar;24(1):203-28.
doi: 10.1016/j.idc.2009.10.001.

Swine Influenza (H1N1) pneumonia: clinical considerations

Burke A Cunha  1
Affiliations
Review

Swine Influenza (H1N1) pneumonia: clinical considerations

Burke A Cunha. Infect Dis Clin North Am. 2010 Mar.

Abstract

Influenza is a viral zoonosis of birds and mammals that has probably existed since antiquity. Attack rates of influenza are relatively high but mortality is relatively low. Influenza mortality is highest in the very young, the very old, and the immunosuppressed. Influenza has the potential for rapid spread and may involve large populations. This article examines the swine influenza (H1N1) strain of recent origin, and compares the microbiology, epidemiology, clinical presentation, differential, clinical, and laboratory diagnosis, therapy, complications, and prognosis with previous recorded outbreaks of avian and human seasonal influenza pneumonias.

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Figures

Fig. 1
Fig. 1
Serial WBC counts in a case of fatal swine influenza (H1N1) pneumonia. (From Cunha BA, Syed U, Mikail N. Rapid clinical diagnosis in fatal swine influenza (H1N1) pneumonia in adult with negative rapid influenza diagnostic tests (RIDTs): diagnostic swine influenza triad. Heart & Lung 2010;39:78–86; with permission.)
Fig. 2
Fig. 2
Relative lymphopenia in a case of fatal swine influenza (H1N1) pneumonia. (From Cunha BA, Syed U, Mickail N, et al. Rapid clinical diagnosis in fatal swine influenza (H1N1) pneumonia in an adult with negative rapid influenza diagnostic tests (RIDTs): Diagnostic swine influenza triad. Heart Lung 2010;39:78–86: with permission.)
Fig. 3
Fig. 3
Serial platelet counts in a case of fatal swine influenza (H1N1) pneumonia. (From Cunha BA, Syed U, Mickail N, et al. Rapid clinical diagnosis in fatal swine influenza (H1N1) pneumonia in an adult with negative rapid influenza diagnostic tests (RIDTs): Diagnostic swine influenza triad. Heart Lung 2010;39:78–86: with permission.)
Fig. 4
Fig. 4
Serial CPK in a case of fatal swine influenza (H1N1) pneumonia. (From Cunha BA, Syed U, Mickail N, et al. Rapid clinical diagnosis in fatal swine influenza (H1N1) pneumonia in an adult with negative rapid influenza diagnostic tests (RIDTs): Diagnostic swine influenza triad. Heart Lung 2010;39:78–86; with permission.)
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