Comment
doi: 10.1038/ncb0310-209.
Epub 2010 Feb 21.
Myc-modulated miR-9 makes more metastases
Affiliations
- PMID: 20173743
- DOI: 10.1038/ncb0310-209
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Comment
Myc-modulated miR-9 makes more metastases
Nat Cell Biol.
2010 Mar.
Abstract
The microRNA miR-9 is induced by Myc in breast cancer cells where it targets the major epithelial adherens junction protein, E-cadherin. This primes the cancer cells for epithelial-mesenchymal transition (EMT) and also stimulates angiogenesis in tumours.
Comment on
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miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis.Nat Cell Biol. 2010 Mar;12(3):247-56. doi: 10.1038/ncb2024. Epub 2010 Feb 21. Nat Cell Biol. 2010. PMID: 20173740 Free PMC article.
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