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. 2010 Mar 15;20(6):1881-4.
doi: 10.1016/j.bmcl.2010.01.159. Epub 2010 Feb 4.

Synthesis, antibacterial and antifungal activities of some carbazole derivatives

Fei-Fei Zhang  1 , Lin-Ling Gan, Cheng-He Zhou
Affiliations

Synthesis, antibacterial and antifungal activities of some carbazole derivatives

Fei-Fei Zhang et al. Bioorg Med Chem Lett. .

Abstract

A series of N-substituted carbazole derivatives were synthesized and evaluated for antibacterial and antifungal activities against Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Bacillus proteus, Candida albicans and Aspergillus fumigatus by two fold serial dilution technique. Some of the synthesized compounds displayed comparable or even better antibacterial and antifungal activities than reference drugs fluconazole, chloramphenicol and norfloxacin against tested strains.

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