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Comment
. 2010 Feb 19;140(4):452-4.
doi: 10.1016/j.cell.2010.02.005.

Primal RNAs: The end of the beginning?

Darryl Conte Jr  1 , Craig C Mello
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Comment

Primal RNAs: The end of the beginning?

Darryl Conte Jr et al. Cell. .
Free article

Abstract

The amplification of small RNAs and the assembly of heterochromatin are mutually dependent processes in fission yeast. But which comes first? Halic and Moazed (2010) propose that primal small RNAs initiate the amplification of small interfering RNAs that drive heterochromatin formation and chromatin silencing.

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