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Review
. 2010 Feb 19;140(4):460-76.
doi: 10.1016/j.cell.2010.01.045.

Lymphangiogenesis: Molecular mechanisms and future promise

Tuomas Tammela  1 , Kari Alitalo
Affiliations
Free article
Review

Lymphangiogenesis: Molecular mechanisms and future promise

Tuomas Tammela et al. Cell. .
Free article

Abstract

The growth of lymphatic vessels (lymphangiogenesis) is actively involved in a number of pathological processes including tissue inflammation and tumor dissemination but is insufficient in patients suffering from lymphedema, a debilitating condition characterized by chronic tissue edema and impaired immunity. The recent explosion of knowledge on the molecular mechanisms governing lymphangiogenesis provides new possibilities to treat these diseases.

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