Phototransduction: keep an eye out for acid-labile TRPs
- PMID: 20178757
- DOI: 10.1016/j.cub.2010.01.013
Phototransduction: keep an eye out for acid-labile TRPs
Abstract
Our mechanistic understanding of phototransduction in the Drosophila eye is still rudimentary. Recent work demonstrates that a combination of phosphoinositide depletion and microvillar acidification is sufficient to activate light-sensitive TRPC channels.
Copyright 2010 Elsevier Ltd. All rights reserved.
Comment on
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Activation of TRP channels by protons and phosphoinositide depletion in Drosophila photoreceptors.Curr Biol. 2010 Feb 9;20(3):189-97. doi: 10.1016/j.cub.2009.12.019. Epub 2010 Jan 28. Curr Biol. 2010. PMID: 20116246
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