Review
doi: 10.1016/j.cub.2010.01.016.
Lipid kinases: charging PtdIns(4,5)P2 synthesis
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- PMID: 20178759
- DOI: 10.1016/j.cub.2010.01.016
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Review
Lipid kinases: charging PtdIns(4,5)P2 synthesis
Curr Biol.
.
Free article
Abstract
Phosphatidylinositol (4,5) bisphosphate is a lipid second messenger that controls diverse cellular processes. Phosphatidylinositolphosphate-5-kinases synthesise this lipid at the plasma membrane, although it is not clear how the localisation of these kinases is controlled. A recent study suggests that the intrinsic surface charge of the plasma membrane may be an important factor.
Copyright 2010 Elsevier Ltd. All rights reserved.
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