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. 2010 Mar 19;12(6):1184-7.
doi: 10.1021/ol902923e.

Gold(I)-catalyzed amination of allylic alcohols with cyclic ureas and related nucleophiles

Paramita Mukherjee  1 , Ross A Widenhoefer
Affiliations

Gold(I)-catalyzed amination of allylic alcohols with cyclic ureas and related nucleophiles

Paramita Mukherjee et al. Org Lett. .

Abstract

A 1:1 mixture of [P(t-Bu)(2)-o-biphenyl]AuCl and AgSbF(6) catalyzes the intermolecular amination of allylic alcohols with 1-methylimidazolidin-2-one and related nucleophiles that, in the case of gamma-unsubstituted or gamma-methyl-substituted allylic alcohols, occurs with high gamma-regioselectivity and syn-stereoselectivity.

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