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Review
. 2010 Feb 8:36:15.
doi: 10.1186/1824-7288-36-15.

Infantile spasms: review of the literature and personal experience

Affiliations
Review

Infantile spasms: review of the literature and personal experience

Alberto Fois. Ital J Pediatr. .

Abstract

This epileptic disorder has become a classic topic for neuropediatricians and the interest is documented by the large number of publications on this subject.The relative frequency among the epileptic syndromes is an another reason why not only neuropediatricians but also general pediatricians must be fully informed about diagnostic, clinical, imaging and genetic aspects.Early diagnosis is of paramount importance in order to obtain even complete results in patients with so called idiopathic situations. A number of problems are still to be solved. There is no agreement on the type and the schedule of treatment. A common denominator about this problem is not jet available even if some advances in this regard have been accomplished. Of paramount importance is an accurate clinical and laboratory examination as a prerequisite regarding prognosis and results of therapy in every single case.However, even if more than 170 years have elapsed since the first communication of dr. West on the peculiar syndrome that his child was suffering of, the interest of scientists on this subject has now been enriched and rewarded.

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Figures

Figure 1
Figure 1
Spontaneous sleep Eight month old male baby. Hypsarrhythmia. Continuous diffuse irregular slow waves mixed with multifocal spikes. Absence of normal sleep features.
Figure 2
Figure 2
Flow chart for treatment of infantile spasms. See details in text.

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References

    1. West WS. On a particular form of infantile convulsions. Lancet. 1841;1:724–725. doi: 10.1016/S0140-6736(00)40184-4. - DOI
    1. Gibbs FA, Gibbs EL. Atlas of Electroencephalography. Vol. 2. Epilepsy Cambridge, MA: Addison Wesley; 1952.
    1. Eling P, Renier WO, Pomper J, Baram TZ. The mystery of Doctor's son, or the riddle of West syndrome. Neurology. 2002;58:953–955. - PMC - PubMed
    1. Shields WD. Infantile spasms: little seizures, BIG consequence. Epilepsy Curr. 2006;6:63–69. doi: 10.1111/j.1535-7511.2006.00100.x. - DOI - PMC - PubMed
    1. Dreifuss FE. Proposal for revised clinical and electroencephalographic classification of epileptic seizures. Epilepsia. 1981;22:249–260. doi: 10.1111/j.1528-1157.1981.tb04106.x. - DOI - PubMed

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